https://www.sec.gov/Archives/edgar/data/906185/000119312518092334/d555678d497.htm497 1 d555678d497.htm 497
Janus Aspen Series
Janus Henderson Balanced Portfolio
Janus Henderson Global Allocation Portfolio - Moderate
Supplement dated March 23, 2018
to Currently Effective Prospectuses
At a special meeting of shareholders of Janus Henderson Global Allocation Portfolio – Moderate held on March 22, 2018, shareholders approved an Agreement and Plan of Reorganization that will result in the transfer of the assets and liabilities of Janus Henderson Global Allocation Portfolio – Moderate to Janus Henderson Balanced Portfolio, effective on or about the close of business on April 27, 2018 (“Closing Date”). As a result, shareholders of Janus Henderson Global Allocation Portfolio – Moderate as of the Closing Date will become shareholders of Janus Henderson Balanced Portfolio, and Janus Henderson Global Allocation Portfolio – Moderate will be terminated.